HIGHLIGHTS

4-in-1 complete oral care

The innovative hybrid brush head features 2 types of bristles on the front for an invigorating tooth clean & gentle gum massage, as well as a tongue and cheek cleaner on the back.

Tough on plaque

Clinically proven to remove 30% more plaque than your regular toothbrush. More durable than nylon bristles, meaning they maintain effectiveness over time without bending or fraying. 100% of users report that issa™ 4 plus is non-abrasive on teeth.

issa™ 4 plus

Real results

Gentle on gums, cheeks & tongue

Clinically proven to reduce gingivitis. Outer silicone bristles prevent you from brushing too hard - which can cause tooth & gum sensitivity. Soft, medical-grade & bacteria-resistant. Gently cleans & massages more sensitive areas of the mouth.

AI Pressure Adapt

issa™ 4 plus analyzes the pressure you’re applying while brushing & auto-adapts the intensity accordingly, for optimal results.

Brush head lasts 2x longer

Environmentally conscious, issa™ 4 plus features a one-of-a-kind, revolutionary hybrid brush head that stays cleaner for longer than traditional toothbrushes - meaning you only need to replace it once every 6 months, instead of every 3 months like most other toothbrushes.

Sonic Pulse technology

Delivers up to 11,000 high-intensity pulsations per minute, creating gentle micro-sweeps that deeply clean teeth, gums, cheeks, and tongue.

4-in-1 complete oral care

The innovative hybrid brush head features 2 types of bristles on the front for an invigorating tooth clean & gentle gum massage, as well as a tongue and cheek cleaner on the back.

Tough on plaque

Clinically proven to remove 30% more plaque than your regular toothbrush. More durable than nylon bristles, meaning they maintain effectiveness over time without bending or fraying. 100% of users report that issa™ 4 plus is non-abrasive on teeth.

Gentle on gums, cheeks & tongue

Clinically proven to reduce gingivitis. Outer silicone bristles prevent you from brushing too hard - which can cause tooth & gum sensitivity. Soft, medical-grade & bacteria-resistant. Gently cleans & massages more sensitive areas of the mouth.

AI Pressure Adapt

issa™ 4 plus analyzes the pressure you’re applying while brushing & auto-adapts the intensity accordingly, for optimal results.

Brush head lasts 2x longer

Environmentally conscious, issa™ 4 plus features a one-of-a-kind, revolutionary hybrid brush head that stays cleaner for longer than traditional toothbrushes - meaning you only need to replace it once every 6 months, instead of every 3 months like most other toothbrushes.

Sonic Pulse technology

Delivers up to 11,000 high-intensity pulsations per minute, creating gentle micro-sweeps that deeply clean teeth, gums, cheeks, and tongue - leaving your mouth feeling fresh and truly clean.

AI Pressure Adapt

One charge. 365 days of power.

issa™ hybrid brush head

3 brushing modes

Whitening

Designed to address moderate tooth discoloration with a higher Sonic Pulse intensity. Restores the natural whiteness of your teeth.

Sensitive

Delivers a lower Sonic Pulse intensity for more sensitive areas of the mouth. Ideal for individuals with gum inflammation or enamel erosion.

Deep Clean

Uses a moderate Sonic Pulse intensity to target stubborn plaque and surface stains. Ideal for hard-to-reach areas and a dentist-level clean at home.

Before

After

BEFORE & AFTER

Clinical results

Based on results from 3rd party clinical testing, in a 4-week trial with twice-daily use.

Improves overall oral hygiene by
140%
in just 1 month.
Reduces gingivitis.
Removes
30%
more plaque than your regular manual toothbrush.
100%
reported whiter teeth and better gum health.

issa™ hybrid brush head

Replace every 6 months

issa™ hybrid brush head combines soft outer silicone bristles that protect sensitive gums with firmer inner polymer bristles that effectively remove plaque and surface stains. Its ultra-hygienic, quick-drying materials resist wear and bacteria build-up, ensuring a more thorough clean every time. For optimal results, replace the brush head every 6 months.

Learn more

FEATURES

One-time
investment

Sustainable
Premium quality & a product life of years. Brush heads last up to 2x longer than other toothbrushes.
Cruelty-free & Vegan
No animals were used in the development and testing of this product.
Staggering battery life
Lasts up to 365 days per single USB charge.
Hygienic & Waterproof
Bacteria-resistant, free of BPA & phthalates, 100% waterproof, easy to clean.

HOW TO USE

Simple & easy

STEP 1

Apply toothpaste

Apply your regular toothpaste to the issa™ brush head. Then press the universal button the turn on issa™ 4 plus, and select your preferred mode if desired in the App.
Download App

STEP 2

Brush

Brush your teeth the same way as you would with a manual toothbrush for 2 minutes. Then use the back of your issa™ 4 plus brush head to gently scrape your tongue and inner cheeks.

STEP 3